![]() ![]() We therefore investigated the validity and reliability of the clinical criteria using a computerized ‘dementia diagnosis system’ for each of 6 sets of criteria to classify a subset (n = 96) of the cases confirmed post-mortem. It was hypothesized that the overall clinical impression may have taken precedence over the use of the actual criteria. Cases who had been diagnosed as NINCDS/ADRDA ‘probable AD’ in life were usually confirmed at autopsy, but half of the NINCDS/ADRDA ‘negative’ cases were not (low specificity). ![]() Data from 204 participants from the Oxford Project to Investigate Memory and Ageing, who were diagnosed post-mortem using the histopathological criteria of the Consortium to Establish a Registry for Alzheimer’s Disease (CERAD), were used to assess the validity of the clinical criteria for Alzheimer’s disease (AD) of the ‘National Institute of Neurological and Communicative Disorders and Stroke/the Alzheimer’s Disease and Related Disorders Association’ (NINCDS/ADRDA). ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |